Myostatin serum concentrations are correlated with the severity of knee osteoarthritis
نویسندگان
چکیده
منابع مشابه
Gremlin-1 Concentrations Are Correlated with the Severity of Knee Osteoarthritis
BACKGROUND Gremlin-1, a bone morphogenetic protein (BMP) antagonist, is up-regulated in osteoarthritis (OA). Therefore, we aim to evaluate the correlation between gremlin-1 concentrations and the onset and severity of OA. MATERIAL AND METHODS We performed this cross-sectional study in a population of 212 patients with knee OA and 125 healthy controls. RESULTS Patients with knee OA had higher se...
متن کاملSerum Interleukin-15 Levels Are Associated with Severity of Pain in Patients with Knee Osteoarthritis
BACKGROUND Inflammation plays a crucial role in the development and progression of osteoarthritis (OA). Interleukin-15 (IL-15) is a well-known proinflammatory cytokine. OBJECTIVE We aimed at evaluating the relationship between serum IL-15 levels and the severity of pain as well as radiographic progression in patients with knee OA. METHODS Two hundred and twenty-six OA patients and 106 contr...
متن کاملSerum and Synovial Fluid Levels of CCL18 are Correlated with Radiographic Grading of Knee Osteoarthritis
BACKGROUND Chemokines are involved in the pathogenesis of osteoarthritis (OA). CCL18, a member of the chemokines family, is observed in synovial fluid (SF) of OA patients. The aim of this study was to determine the association between CCL18 levels in serum and SF with radiographic knee OA. MATERIAL AND METHODS This study was conducted in a population of 308 patients with knee OA. The radiolog...
متن کاملAssociation of follistatin-like 3 concentrations in serum and synovial fluid with the radiographic severity of knee osteoarthritis.
OBJECTIVE Follistatin-like 3 (FSTL3), a circulating glycoprotein, is correlated with obesity and inflammation, which are potential mechanisms of osteoarthritis (OA). This study aims to determine the correlation of FSTL3 concentrations in serum and synovial fluid (SF) with the radiographic severity of OA. METHODS This study consisted of 200 patients with knee OA and 148 healthy controls. The r...
متن کاملPlasma and synovial fluid connective tissue growth factor levels are correlated with disease severity in patients with knee osteoarthritis.
BACKGROUND Connective tissue growth factor (CTGF) has been implicated in development of osteoarthritis (OA). OBJECTIVE To determine the correlation between plasma and synovial fluid CTGF levels and the severity in knee osteoarthritis patients. METHODS A total of 100 subjects were recruited into this study (75 OA patients and 25 controls). CTGF concentrations in plasma and synovial fluid wer...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Laboratory Analysis
سال: 2016
ISSN: 0887-8013
DOI: 10.1002/jcla.22094